It’s almost half a year since our last update. We hope that you all are in good health and doing well.
In the meantime, we have read and analysed the R&D projects that we received after our call for projects and selected to continue with two of them.
One project solely funded by Eye Hope Foundation is continuing the work by M. Plaas in Estonia on the WFS1 rat. In my opinion this is still the best animal model available to date of Wolfram Syndrome. The project will evaluate neutrophic factors, look at GLP1 / GIP co-agonists and gene therapy as a treatment for Wolfram syndrome. With their established baseline from the previous projects, they have a good comparison base.
Another project was picked in cooperation with the Snow Foundation where we will fund part of the work by B. Delprat and his team in Montpellier. The project also uses gene therapy for administering a protein in a mouse model of WFS1. In parallel the group looks also at a zebrafish model of WFS1.
We wish that we could fund many more projects but after a corona year we are happy we can contribute at least a bit of funding to these two groups.
Besides trying to find a better treatment and managing our daily lives, we as parents have a duty to prepare our kids for the future. Victor is a very positive boy and attending sixth grade in the local international school. As a preparation for the transition to the Middle Years Program, he completed his exhibition project. As a topic of choice, he focused on different types of syndromes (“No surprise”). As part of his work, he performed a 24 km sponsored walk for Eye Hope Foundation collecting a significant amount of funding. He got excellent grades and below are screenshots of his first and last page.
We are very proud of his attitude in life.
On behalf of Eye Hope Foundation,